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Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.
Human monocytes cultured on adherent IgG produce a specific IL-1 inhibitor that functions as a receptor antagonist (IL-1ra). This molecular has been purified, sequenced, cloned as a cDNA, and expressed in Escherichia coli. Recombinant IL-1ra has 17,000 mol wt and binds to IL-1 receptors on T lymphoc...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2139669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114622 |
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