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Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

Human monocytes cultured on adherent IgG produce a specific IL-1 inhibitor that functions as a receptor antagonist (IL-1ra). This molecular has been purified, sequenced, cloned as a cDNA, and expressed in Escherichia coli. Recombinant IL-1ra has 17,000 mol wt and binds to IL-1 receptors on T lymphoc...

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Autors principals: Arend, W P, Welgus, H G, Thompson, R C, Eisenberg, S P
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC296623/
https://ncbi.nlm.nih.gov/pubmed/2139669
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