Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

Human monocytes cultured on adherent IgG produce a specific IL-1 inhibitor that functions as a receptor antagonist (IL-1ra). This molecular has been purified, sequenced, cloned as a cDNA, and expressed in Escherichia coli. Recombinant IL-1ra has 17,000 mol wt and binds to IL-1 receptors on T lymphoc...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Arend, W P, Welgus, H G, Thompson, R C, Eisenberg, S P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296623/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2139669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114622
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