Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms.

Lipopolysaccharide (LPS) treatment of monocytic cells has been shown to activate the Raf-1/mitogen-activated protein kinase (MAPK) signaling pathway and to increase secretory interleukin-1 receptor antagonist (sIL-1Ra) gene expression. The significance of the activation of the Raf-1/MAPK signaling p...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Guthridge, C J, Eidlen, D, Arend, W P, Gutierrez-Hartmann, A, Smith, M F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1118
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