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Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms.

Lipopolysaccharide (LPS) treatment of monocytic cells has been shown to activate the Raf-1/mitogen-activated protein kinase (MAPK) signaling pathway and to increase secretory interleukin-1 receptor antagonist (sIL-1Ra) gene expression. The significance of the activation of the Raf-1/MAPK signaling p...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphov: Guthridge, C J, Eidlen, D, Arend, W P, Gutierrez-Hartmann, A, Smith, M F
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1118
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