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Effect of Sensor Domain Mutations on the Properties of Voltage-Gated Ion Channels: Molecular Dynamics Studies of the Potassium Channel Kv1.2

The effects on the structural and functional properties of the Kv1.2 voltage-gated ion channel, caused by selective mutation of voltage sensor domain residues, have been investigated using classical molecular dynamics simulations. Following experiments that have identified mutations of voltage-gated...

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Bibliografski detalji
Glavni autori: Delemotte, Lucie, Treptow, Werner, Klein, Michael L., Tarek, Mounir
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966007/
https://ncbi.nlm.nih.gov/pubmed/21044565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.069
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