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Initial Response of the Potassium Channel Voltage Sensor to a Transmembrane Potential

Early transition events of the voltage sensor (VS) of Kv1.2 potassium channel embedded in a lipid membrane are triggered using full atomistic molecular dynamics (MD) simulations. When subject to an applied hyperpolarized transmembrane (TM) voltage, the VS undergoes conformational changes and reaches...

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Bibliographic Details
Main Authors: Treptow, Werner, Tarek, Mounir, Klein, Michael L.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668160/
https://ncbi.nlm.nih.gov/pubmed/19175309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807330g
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