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Coupled Motions between Pore and Voltage-Sensor Domains: A Model for Shaker B, a Voltage-Gated Potassium Channel

A high-resolution crystal structure of KvAP, an archeabacterial voltage-gated potassium (Kv) channel, complexed with a monoclonal Fab fragment has been recently determined. Based on this structure, a mechanism for the activation (opening) of Kv channels has been put forward. This mechanism has since...

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Hlavní autoři: Treptow, Werner, Maigret, Bernard, Chipot, Christophe, Tarek, Mounir
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304659/
https://ncbi.nlm.nih.gov/pubmed/15454436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039628
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