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Fibulin-1 is required for morphogenesis of neural crest-derived structures
Here we report that mouse embryos homozygous for a gene trap insertion in the fibulin-1 (Fbln1) gene are deficient in Fbln1 and exhibit cardiac ventricular wall thinning and ventricular septal defects with double outlet right ventricle or overriding aorta. Fbln1 nulls also display anomalies of aorti...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965525/ https://ncbi.nlm.nih.gov/pubmed/18538758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.04.029 |
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