Fibulin-1 is required for morphogenesis of neural crest-derived structures

Here we report that mouse embryos homozygous for a gene trap insertion in the fibulin-1 (Fbln1) gene are deficient in Fbln1 and exhibit cardiac ventricular wall thinning and ventricular septal defects with double outlet right ventricle or overriding aorta. Fbln1 nulls also display anomalies of aorti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cooley, Marion A., Kern, Christine B., Fresco, Victor M., Wessels, Andy, Thompson, Robert P., McQuinn, Tim C., Twal, Waleed O., Mjaatvedt, Corey H., Drake, Christopher J., Argraves, W. Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965525/
https://ncbi.nlm.nih.gov/pubmed/18538758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.04.029
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