Characterization and Epitope Mapping of Human Monoclonal Antibodies to PDC-E2, the Immunodominant Autoantigen of Primary Biliary Cirrhosis

Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient with PBC with the mouse human heterohybrid ce...

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Autores principales: Leung, Patrick S. C., Krams, Sheri, Munoz, Santiago, Surh, Charles P., Ansari, Aftab, Kenny, Thomas, Robbins, Dick L., Fung, John, Starzl, Thomas E., Maddrey, Willis, Coppel, Ross L., Gershwin, M. Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965520/
https://ncbi.nlm.nih.gov/pubmed/1283300
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