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Characterization and Epitope Mapping of Human Monoclonal Antibodies to PDC-E2, the Immunodominant Autoantigen of Primary Biliary Cirrhosis
Further to define the epitopes of PDC-E2, the major autoantigen in primary biliary cirrhosis (PBC), we have developed and characterized five human monoclonal antibodies. These antibodies were derived by fusing a regional hepatic lymph node from a patient with PBC with the mouse human heterohybrid ce...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1992
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965520/ https://ncbi.nlm.nih.gov/pubmed/1283300 |
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