Kinetic Evidence that Allosteric Activation of Antithrombin by Heparin Is Mediated by Two Sequential Conformational Changes

Lignende værker

• Antiangiogenic forms of antithrombin specifically bind to the anticoagulant heparin sequence
  af: Schedin-Weiss, Sophia, et al.
  Udgivet: (2008)
• COOPERATIVE INTERACTIONS OF THREE HOTSPOT HEPARIN BINDING RESIDUES ARE CRITICAL FOR ALLOSTERIC ACTIVATION OF ANTITHROMBIN BY HEPARIN
  af: Richard, Benjamin, et al.
  Udgivet: (2018)
• The Signature 3-O-Sulfo Group of the Anticoagulant Heparin Sequence Is Critical for Heparin Binding to Antithrombin but Is Not Required for Allosteric Activation
  af: Richard, Benjamin, et al.
  Udgivet: (2009)
• Characterization of the Conformational Alterations, Reduced Anticoagulant Activity, and Enhanced Antiangiogenic Activity of Prelatent Antithrombin
  af: Richard, Benjamin, et al.
  Udgivet: (2008)
• Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. a paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors
  af: Olson, Steven T., et al.
  Udgivet: (2010)