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A switch-on mechanism to activate maize ribosome-inactivating protein for targeting HIV-infected cells
Maize ribosome-inactivating protein (RIP) is a plant toxin that inactivates eukaryotic ribosomes by depurinating a specific adenine residue at the α-sarcin/ricin loop of 28S rRNA. Maize RIP is first produced as a proenzyme with a 25-amino acid internal inactivation region on the protein surface. Dur...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965250/ https://ncbi.nlm.nih.gov/pubmed/20558598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq551 |
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