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Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins

Ribosome-inactivating proteins (RIPs) including ricin, Shiga toxin, and trichosanthin, are RNA N-glycosidases that depurinate a specific adenine residue (A-4324 in rat 28S ribosomal RNA, rRNA) in the conserved α-sarcin/ricin loop (α-SRL) of rRNA. RIPs are grouped into three types according to the nu...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Shi, Wei-Wei, Mak, Amanda Nga-Sze, Wong, Kam-Bo, Shaw, Pang-Chui
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273143/
https://ncbi.nlm.nih.gov/pubmed/27879643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21111588
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