The Recombinant Maize Ribosome-Inactivating Protein Transiently Reduces Viral Load in SHIV89.6 Infected Chinese Rhesus Macaques

Ribosome inactivating proteins (RIPs) inhibit protein synthesis by depurinating the large ribosomal RNA and some are found to possess anti-human immunodeficiency virus (HIV) activity. Maize ribosome inactivating protein (RIP) has an internal inactivation loop which is proteolytically removed for ful...

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Veröffentlicht in:Toxins (Basel)
Hauptverfasser: Wang, Rui-Rui, Au, Ka-Yee, Zheng, Hong-Yi, Gao, Liang-Min, Zhang, Xuan, Luo, Rong-Hua, Law, Sue Ka-Yee, Mak, Amanda Nga-Sze, Wong, Kam-Bo, Zhang, Ming-Xu, Pang, Wei, Zhang, Gao-Hong, Shaw, Pang-Chui, Zheng, Yong-Tang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303820/
https://ncbi.nlm.nih.gov/pubmed/25606813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7010156
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