ATM Modulates the Loading of Recombination Proteins onto a Chromosomal Translocation Breakpoint Hotspot

Chromosome translocations induced by DNA damaging agents, such as ionizing radiation and certain chemotherapies, alter genetic information resulting in malignant transformation. Abrogation or loss of the ataxia-telangiectasia mutated (ATM) protein, a DNA damage signaling regulator, increases the inc...

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Detalhes bibliográficos
Main Authors: Sun, Jiying, Oma, Yukako, Harata, Masahiko, Kono, Kazuteru, Shima, Hiroki, Kinomura, Aiko, Ikura, Tsuyoshi, Suzuki, Hidekazu, Mizutani, Shuki, Kanaar, Roland, Tashiro, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965082/
https://ncbi.nlm.nih.gov/pubmed/21048951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013554
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