Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase

A balanced deoxyribonucleotide (dNTP) supply is essential for DNA repair. Here, we found that ribonucleotide reductase (RNR) subunits RRM1 and RRM2 accumulated very rapidly at damage sites. RRM1 bound physically to Tip60. Chromatin immunoprecipitation analyses of cells with an I-SceI cassette reveal...

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保存先:
書誌詳細
主要な著者: Niida, Hiroyuki, Katsuno, Yuko, Sengoku, Misuzu, Shimada, Midori, Yukawa, Megumi, Ikura, Masae, Ikura, Tsuyoshi, Kohno, Kazuteru, Shima, Hiroki, Suzuki, Hidekazu, Tashiro, Satoshi, Nakanishi, Makoto
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2010
主題:
Research Communication
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816732/
https://ncbi.nlm.nih.gov/pubmed/20159953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1863810
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