Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations

Chromosomal translocations are hallmarks of various types of cancers and leukemias. However, the molecular mechanisms of chromosome translocations remain largely unknown. The ataxia-telangiectasia mutated (ATM) protein, a DNA damage signaling regulator, facilitates DNA repair to prevent chromosome a...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Sun, Jiying, Shi, Lin, Kinomura, Aiko, Fukuto, Atsuhiko, Horikoshi, Yasunori, Oma, Yukako, Harata, Masahiko, Ikura, Masae, Ikura, Tsuyoshi, Kanaar, Roland, Tashiro, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953535/
https://ncbi.nlm.nih.gov/pubmed/29759113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32222
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