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Infusion of mature megakaryocytes into mice yields functional platelets

Thrombopoiesis, the process by which circulating platelets arise from megakaryocytes, remains incompletely understood. Prior studies suggest that megakaryocytes shed platelets in the pulmonary vasculature. To better understand thrombopoiesis and to develop a potential platelet transfusion strategy t...

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Detalhes bibliográficos
Main Authors: Fuentes, Rudy, Wang, Yuhuan, Hirsch, Jessica, Wang, Cheng, Rauova, Lubica, Worthen, G. Scott, Kowalska, M. Anna, Poncz, Mortimer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964983/
https://ncbi.nlm.nih.gov/pubmed/20972336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43326
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