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Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets

The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. The characterization of physical mixture of drug and organic acids was performed b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sateesha, SB, Rajamma, AJ, Narode, MK, Vyas, BD
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Medknow Publications 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964766/
https://ncbi.nlm.nih.gov/pubmed/21042476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-1483.66793
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