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Drug Release Kinetics and Front Movement in Matrix Tablets Containing Diltiazem or Metoprolol/λ-Carrageenan Complexes

In this work we investigated the moving boundaries and the associated drug release kinetics in matrix tablets prepared with two complexes between λ-carrageenan and two soluble model drugs, namely, diltiazem HCl and metoprolol tartrate aiming at clarifying the role played by drug/polymer interaction...

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Detalhes bibliográficos
Principais autores: Bettini, Ruggero, Bonferoni, Maria Cristina, Colombo, Paolo, Zanelotti, Laura, Caramella, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090483/
https://ncbi.nlm.nih.gov/pubmed/25045689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/671532
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