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Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets

The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. The characterization of physical mixture of drug and organic acids was performed b...

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Detalhes bibliográficos
Main Authors: Sateesha, SB, Rajamma, AJ, Narode, MK, Vyas, BD
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964766/
https://ncbi.nlm.nih.gov/pubmed/21042476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-1483.66793
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