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Development and in vitro evaluation of an oral floating matrix tablet formulation of diltiazem hydrochloride

The purpose of this research was to prepare a floating drug delivery system of diltiazem hydrochloride (DTZ). Floating matrix tablets of DTZ were developed to prolong gastric residence time and increase its bioavailability. Rapid gastrointestinal transit could result in incomplete drug release from...

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Autors principals: Gambhire, Manoj N., Ambade, Kshitij W., Kurmi, Sushma D., Kadam, Vilasrao J., Jadhav, Kisan R.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750569/
https://ncbi.nlm.nih.gov/pubmed/17915823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0803073
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