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Development of sustained-release floating tablets of diltiazem hydrochloride

Diltiazem hydrochloride (DTZ), utilised for cardiovascular conditions, possesses a short half-life, necessitating frequent dosing. To enhance compliance, sustainedrelease (SR) floating tablets were developed using a Quality by Design (QbD) approach. This study aimed to formulate DTZ 120 mg tablets,...

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Principais autores: Hung Pham Van, Tung Nguyen Thanh, Nhat Hoang Thi Anh, Hieu Bui Trung, Uyen Dinh Thi Thu, Duyen Nguyen Thi Thanh
Formato: Artigo
Idioma:Inglês
Publicado em: Vietnam Ministry of Science and Technology 2025-07-01
coleção:Vietnam Journal of Science, Technology and Engineering
Assuntos:
diltiazem hydrochloride
floating
quality by design
sustained-release
tablets
Acesso em linha:https://vietnamscience.vjst.vn/index.php/vjste/article/view/1309
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