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PYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM

Amyloid molecules harboring pyroglutamate (pGlu) residue at the N-termini are considered to be important for the development of cerebral amyloidosis such as Alzheimer’s disease and thought to be either spontaneously generated or being catalyzed by glutaminyl cyclase. Familial British dementia (FBD)...

詳細記述

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書誌詳細
主要な著者: Tomidokoro, Yasushi, Tamaoka, Akira, Holton, Janice L., Lashley, Tammaryn, Frangione, Blas, Revesz, Tamas, Rostagno, Agueda, Ghiso, Jorge
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964672/
https://ncbi.nlm.nih.gov/pubmed/21037969
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