Regional Distribution of Amyloid-Bri Deposition and Its Association with Neurofibrillary Degeneration in Familial British Dementia

Familial British dementia (FBD), pathologically characterized by cerebral amyloid angiopathy (CAA), amyloid plaques, and neurofibrillary degeneration, is associated with a stop codon mutation in the BRI gene resulting in the production of an amyloidogenic fragment, amyloid-Bri (ABri). The aim of thi...

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Detalhes bibliográficos
Main Authors: Holton, Janice L., Ghiso, Jorge, Lashley, Tammaryn, Rostagno, Agueda, Guerin, Christopher J., Gibb, Graham, Houlden, Henry, Ayling, Hilary, Martinian, Lillian, Anderton, Brian H., Wood, Nicholas W., Vidal, Ruben, Plant, Gordon, Frangione, Blas, Revesz, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850296/
https://ncbi.nlm.nih.gov/pubmed/11159188
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