Regional Distribution of Amyloid-Bri Deposition and Its Association with Neurofibrillary Degeneration in Familial British Dementia

Familial British dementia (FBD), pathologically characterized by cerebral amyloid angiopathy (CAA), amyloid plaques, and neurofibrillary degeneration, is associated with a stop codon mutation in the BRI gene resulting in the production of an amyloidogenic fragment, amyloid-Bri (ABri). The aim of thi...

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Autors principals: Holton, Janice L., Ghiso, Jorge, Lashley, Tammaryn, Rostagno, Agueda, Guerin, Christopher J., Gibb, Graham, Houlden, Henry, Ayling, Hilary, Martinian, Lillian, Anderton, Brian H., Wood, Nicholas W., Vidal, Ruben, Plant, Gordon, Frangione, Blas, Revesz, Tamas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2001
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850296/
https://ncbi.nlm.nih.gov/pubmed/11159188
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