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Shortcomings of short hairpin RNA-based transgenic RNA interference in mouse oocytes
BACKGROUND: RNA interference (RNAi) is a powerful approach to study a gene function. Transgenic RNAi is an adaptation of this approach where suppression of a specific gene is achieved by expression of an RNA hairpin from a transgene. In somatic cells, where a long double-stranded RNA (dsRNA) longer...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964603/ https://ncbi.nlm.nih.gov/pubmed/20939886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-9-8 |
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