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Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unl...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Taborska, Eliska, Pasulka, Josef, Malik, Radek, Horvat, Filip, Jenickova, Irena, Jelić Matošević, Zoe, Svoboda, Petr
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944382/
https://ncbi.nlm.nih.gov/pubmed/31860668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008261
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