Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unl...

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Udgivet i:PLoS Genet
Main Authors: Taborska, Eliska, Pasulka, Josef, Malik, Radek, Horvat, Filip, Jenickova, Irena, Jelić Matošević, Zoe, Svoboda, Petr
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944382/
https://ncbi.nlm.nih.gov/pubmed/31860668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008261
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