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Main constraints for RNAi induced by expressed long dsRNA in mouse cells
RNAi is the sequence-specific mRNA degradation guided by siRNAs produced from long dsRNA by RNase Dicer. Proteins executing RNAi are present in mammalian cells but rather sustain the microRNA pathway. Aiming for a systematic analysis of mammalian RNAi, we report here that the main bottleneck for RNA...
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| Publicado en: | Life Sci Alliance |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Life Science Alliance LLC
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6391682/ https://ncbi.nlm.nih.gov/pubmed/30808654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800289 |
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