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microRNA activity is suppressed in mouse oocytes
MicroRNAs (miRNAs) are small endogenous RNAs, which typically imperfectly base-pair with 3′UTRs and mediate translational repression and mRNA degradation. Dicer, an RNase III generating small RNAs in the miRNA and RNAi pathways, is essential for meiotic maturation of mouse oocytes. We found that 3′U...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2010
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824427/ https://ncbi.nlm.nih.gov/pubmed/20116252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.12.042 |
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