Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation

Recently, several cases of fatal lymphocytic choriomeningitis virus (LCMV) infection occurred in transplant recipients being treated with the immunosuppressive calcineurin inhibitor FK506. These findings were surprising because LCMV is a noncytolytic virus. To understand how a noncytolytic virus can...

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Bibliographische Detailangaben
Hauptverfasser: Araki, Koichi, Gangappa, Shivaprakash, Dillehay, Dirck L., Rouse, Barry T., Larsen, Christian P., Ahmed, Rafi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964579/
https://ncbi.nlm.nih.gov/pubmed/20921283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100124
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