Immunotherapy with Tacrolimus (FK506) Does Not Select for Resistance to Calcineurin Inhibitors in Candida albicans Isolates from Liver Transplant Patients

In Candida albicans, calcineurin mediates tolerance to azole antifungal drugs, survival in serum, and virulence. In this study, we examined 24 Candida isolates from liver transplant recipients receiving a calcineurin inhibitor as a component of their immunosuppressive therapy. We were unable to dete...

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Detalhes bibliográficos
Main Authors: Reedy, Jennifer L., Husain, Shahid, Ison, Michael, Pruett, Timothy L., Singh, Nina, Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426937/
https://ncbi.nlm.nih.gov/pubmed/16569889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1573-1577.2006
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