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Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?
The drugs cyclosporine A (CsA) and tacrolimus (FK506) revolutionized organ transplantation. Both compounds are still widely used in the clinic as well as for basic research, even though they have dramatic side effects and modulate other pathways than calcineurin-NFATc, too. To answer the major open...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774854/ https://ncbi.nlm.nih.gov/pubmed/19860902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-7-25 |
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