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Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation

Recently, several cases of fatal lymphocytic choriomeningitis virus (LCMV) infection occurred in transplant recipients being treated with the immunosuppressive calcineurin inhibitor FK506. These findings were surprising because LCMV is a noncytolytic virus. To understand how a noncytolytic virus can...

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Main Authors: Araki, Koichi, Gangappa, Shivaprakash, Dillehay, Dirck L., Rouse, Barry T., Larsen, Christian P., Ahmed, Rafi
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964579/
https://ncbi.nlm.nih.gov/pubmed/20921283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100124
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