Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment

Toll-like receptors (TLRs) are mediators of innate immune responses detecting conserved pathogen-associated molecules. Whereas most TLRs are expressed on the cell surface, TLR3, 7, 8 and 9 are predominantly localized in endosomal compartments. Recent studies reported that TLRs are also expressed by...

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Main Authors: Richardt-Pargmann, Denise, Wechsler, Miriam, Krieg, Arthur M., Vollmer, Jörg, Jurk, Marion
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964431/
https://ncbi.nlm.nih.gov/pubmed/20542588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2010.03.011
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