Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies to certain cellular macromolecules, such as the small nuclear ribonucleoprotein particles (snRNPs), which had been considered to be passive targets of the autoimmune response. SLE is also ch...

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Autors principals: Vollmer, Jörg, Tluk, Sibylle, Schmitz, Claudia, Hamm, Svetlana, Jurk, Marion, Forsbach, Alexandra, Akira, Shizuo, Kelly, Kindra M., Reeves, Westley H., Bauer, Stefan, Krieg, Arthur M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213330/
https://ncbi.nlm.nih.gov/pubmed/16330816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051696
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