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Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment
Toll-like receptors (TLRs) are mediators of innate immune responses detecting conserved pathogen-associated molecules. Whereas most TLRs are expressed on the cell surface, TLR3, 7, 8 and 9 are predominantly localized in endosomal compartments. Recent studies reported that TLRs are also expressed by...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964431/ https://ncbi.nlm.nih.gov/pubmed/20542588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2010.03.011 |
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