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Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses

The ability of the host to distinguish between self and foreign nucleic acids is one of the critical factors contributing to the recognition of pathogens by Toll-like receptors (TLRs). Under certain circumstances, eukaryotic self-RNA may reach TLR-containing compartments allowing for self-recognitio...

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Detalhes bibliográficos
Main Authors: Tluk, Sibylle, Jurk, Marion, Forsbach, Alexandra, Weeratna, Risini, Samulowitz, Ulrike, Krieg, Arthur M., Bauer, Stefan, Vollmer, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733840/
https://ncbi.nlm.nih.gov/pubmed/19332442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp030
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