Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses

The ability of the host to distinguish between self and foreign nucleic acids is one of the critical factors contributing to the recognition of pathogens by Toll-like receptors (TLRs). Under certain circumstances, eukaryotic self-RNA may reach TLR-containing compartments allowing for self-recognitio...

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Bibliographic Details
Main Authors: Tluk, Sibylle, Jurk, Marion, Forsbach, Alexandra, Weeratna, Risini, Samulowitz, Ulrike, Krieg, Arthur M., Bauer, Stefan, Vollmer, Jörg
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Original Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733840/
https://ncbi.nlm.nih.gov/pubmed/19332442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp030
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