NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

Cardiac failure occurs when the heart fails to adapt to chronic stresses. Reactive oxygen species (ROS)-dependent signaling is implicated in cardiac stress responses, but the role of different ROS sources remains unclear. Here we report that NADPH oxidase-4 (Nox4) facilitates cardiac adaptation to c...

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Main Authors: Zhang, Min, Brewer, Alison C., Schröder, Katrin, Santos, Celio X. C., Grieve, David J., Wang, Minshu, Anilkumar, Narayana, Yu, Bin, Dong, Xuebin, Walker, Simon J., Brandes, Ralf P., Shah, Ajay M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964252/
https://ncbi.nlm.nih.gov/pubmed/20921387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009700107
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