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NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

Glutathione is the major intracellular redox buffer in the liver and is critical for hepatic detoxification of xenobiotics and other environmental toxins. Hepatic glutathione is also a major systemic store for other organs and thus impacts on pathologies such as Alzheimer's disease, Sickle Cell...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Murray, Thomas V.A., Dong, Xuebin, Sawyer, Greta J., Caldwell, Anna, Halket, John, Sherwood, Roy, Quaglia, Alberto, Dew, Tracy, Anilkumar, Narayana, Burr, Simon, Mistry, Rajesh K., Martin, Daniel, Schröder, Katrin, Brandes, Ralf P., Hughes, Robin D., Shah, Ajay M., Brewer, Alison C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698376/
https://ncbi.nlm.nih.gov/pubmed/26472193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.09.015
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