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Par3 Controls Spindle Pole Orientation in Epithelial Cells by aPKC-Mediated Phosphorylation of Pins at the Apical Cortex
BACKGROUND: Formation of epithelial sheets requires that cell division occurs in the plane of the sheet. During mitosis, spindle poles align so the astral microtubules contact the lateral cortex. Confinement of the mammalian Pins protein to the lateral cortex is essential for this process. Defects i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963683/ https://ncbi.nlm.nih.gov/pubmed/20933426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.09.032 |
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