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aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells

Bazooka (PAR-3), PAR-6, and aPKC form a complex that plays a key role in the polarization of many cell types. In epithelial cells, however, Bazooka localizes below PAR-6 and aPKC at the apical/lateral junction. Here, we show that Baz is excluded from the apical aPKC domain in epithelia by aPKC phosp...

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Autori principali: Morais-de-Sá, Eurico, Mirouse, Vincent, St Johnston, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885938/
https://ncbi.nlm.nih.gov/pubmed/20434988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.040
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