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Comprehensive structural and functional characterization of the human kinome by protein structure modeling and ligand virtual screening
The growing interest in the identification of kinase inhibitors, promising therapeutics in the treatment of many diseases, has created a demand for the structural characterization of the entire human kinome. At the outset of the drug development process, the lead-finding stage, approaches that enric...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963673/ https://ncbi.nlm.nih.gov/pubmed/20853887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci100235n |
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