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Comparison of structure- and threading-based approaches to protein functional annotation

To exploit the vast amount of sequence information provided by the Genomic revolution, the biological function of these sequences must be identified. As a practical matter, this is often accomplished by functional inference. Purely sequence-based approaches, particularly in the “twilight zone” of lo...

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Dettagli Bibliografici
Autori principali: Brylinski, Michal, Skolnick, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804779/
https://ncbi.nlm.nih.gov/pubmed/19731377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22566
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