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Cross-reactivityvirtual profiling of the human kinome by X-React(KIN) – a Chemical Systems Biology approach
Many drug candidates fail in clinical development due to their insufficient selectivity that may cause undesired side effects. Therefore, modern drug discovery is routinely supported by computational techniques, which can identify alternate molecular targets with a significant potential for cross-re...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997910/ https://ncbi.nlm.nih.gov/pubmed/20958088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp1002976 |
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