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When the Optimal Is Not the Best: Parameter Estimation in Complex Biological Models

BACKGROUND: The vast computational resources that became available during the past decade enabled the development and simulation of increasingly complex mathematical models of cancer growth. These models typically involve many free parameters whose determination is a substantial obstacle to model de...

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Bibliografski detalji
Glavni autori: Fernández Slezak, Diego, Suárez, Cecilia, Cecchi, Guillermo A., Marshall, Guillermo, Stolovitzky, Gustavo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963600/
https://ncbi.nlm.nih.gov/pubmed/21049094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013283
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