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Parameter Estimation and Model Selection in Computational Biology

A central challenge in computational modeling of biological systems is the determination of the model parameters. Typically, only a fraction of the parameters (such as kinetic rate constants) are experimentally measured, while the rest are often fitted. The fitting process is usually based on experi...

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Bibliografiske detaljer
Main Authors: Lillacci, Gabriele, Khammash, Mustafa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832681/
https://ncbi.nlm.nih.gov/pubmed/20221262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000696
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