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Optimal experiment selection for parameter estimation in biological differential equation models
BACKGROUND: Parameter estimation in biological models is a common yet challenging problem. In this work we explore the problem for gene regulatory networks modeled by differential equations with unknown parameters, such as decay rates, reaction rates, Michaelis-Menten constants, and Hill coefficient...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536579/ https://ncbi.nlm.nih.gov/pubmed/22838836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-181 |
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